Soluble Relaxing Factor from Muscle
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چکیده
منابع مشابه
Soluble Relaxing Factor from Muscle*
Gergely, Briggs, and Kaldor (24) have recently shown that the so called Marsh-Bendall relaxing factor consists of a granular component and a heat labile dialyzable cofactor. The requirement for both components could be demonstrated for the inhibition of Mg++-activated myofibrillar adenosine triphosphatase, for the inhibition of the adenosine triphosphate-induced syneresis of myofibrils and for ...
متن کاملThe Nature of the Muscle-Relaxing Factor
Analysis of the effects of deoxycholate and benzalkonium chloride on granule relaxing activity, myofibril and glycerinated fiber responses to ATP, and the sensitivity of these actomyosin-containing systems to relaxing factors have established that it is possible to differentially inactivate intrinsic granule relaxing factor. It is therefore possible to use these agents to treat myofibrils and g...
متن کاملIntracellular localization of the skeletal-muscle relaxing factor.
Mandeles, S. (1960). J. Chromat. 3, 256. Mandeles, S. & Ducay, E. D. (1961). Fed. Proc. 20, 389. Marshall,M.E. & Deutsch,H. F. (1951). J. biol. Chem. 189,1. Oncley, J. L., Scatchard, G. & Brown, A. (1947). J. phys. chem. 51, 184. Parker, W. C. & Beam, A. G. (1961). Science, 133, 1014. Poulik, M. (1959). J. Immunol. 82, 502. Rhodes, M. B., Azari, P. R. & Feeney, R. E. (1958). J. biol. Chem. 230,...
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Background and Purpose: We investigated the chemical identity of the endothelium-derived relaxing factor generated by acetylcholine in cerebral microvessels by studying the effects and mechanism of action of inhibitors of nitric oxide synthesis from arginine on the vasodilation and endothelium-derived relaxing factor production induced by topical application of acetylcholine in cerebral arterio...
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The vascular effects of endothelin-1 (ET) in humans were investigated by brachial artery infusions of ET into 25 healthy volunteers. Forearm blood flow increased from a mean±SD value of 2.3± 1.5 to 2.5± 1.5 ml/min/100 ml forearm tissue (n=25, p<0.05) in response to low dose (0.5 ng/min/100 ml forearm tissue) ET infusion and decreased to 1.78±1.3 and 1.1±0.9 ml/min/100 ml forearm tissue (p<0.001...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1960
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64488-6